OEH

Pharmacoepidemiology,causal inference,real-world evidence.

01 / Pharmacoepidemiology · Real-world evidence · Teaching
Research Studies Manager, lecturer and pharmacoepidemiologist. Six projects follow.

Design precedes analysis.

Exposure, outcome, the confounders between them and a defined time zero: each study begins with a causal diagram before any model is fitted.

Z
Instrument
A
Exposure
L
Confounders
Y
Outcome
M
Mediator

Capabilities

Clinical
Research
Inpatient rounds~60 patients a day · MSc rotations
Drug-utilisation reviewQueries resolved in 15 min on average
Ethics reviewFive-member IRB · SOPs · Post-approval oversight
Study managementTen concurrent studies · GCP · Budgets
Target trial emulationEligibility · Assignment · Time zero
Causal inferenceConfounding · Immortal time · DAGs
Survival & psychometricsKaplan–Meier · Cox · Factor structure
Global Burden of Disease204 countries · 811 locations
TeachingNine courses · 100+ competency assessments
01 / Real-world evidence
7,069 lung-cancer admissions from a 360,000-record EHR dataset: supportive-medication dosing and what happens next.

Cohort

Records · Pipeline
Raw records360,000
Lung-cancer cases7,069
Exposure windowsDerived
7,069
Analysis-ready
Explore project ↗
02 / Causal inference
Donepezil versus memantine in hypertensive Alzheimer's disease, emulated as the trial that would have been run. ISPE 2025.

Trial

Protocol · Time zero
EligibilityDefined
Strategies2 arms
Follow-up12 months
t₀
One time zero
Read the abstract ↗
03 / Global Burden of Disease
Twelve consortium papers in The Lancet and JACC: 204 countries, 811 subnational locations, 20,000 citations and counting.

Atlas

Lancet · 2024
AMR deaths, 20211.14 million
Forecast 20501.91 million
Citations5,911
204
Countries and territories
See the papers ↗
04 / Health literacy
The Literacy Assessment of Hypertension Tool in Arabic: translated, culturally adapted, validated. First place, AAU 2024.

Literacy

Instrument · Arabic
Forward translationDone
Back translationDone
Expert reviewDone
Pre-testPatients
1st
Clinical pharmacy · AAU 2024
Read the story ↗
05 / Research operations
Three in-house apps carry data collection at Orthocure: 40% less workload, 98% patient follow-up, ten studies running at once.

Apps

Follow-up
Workload−40%
Patient follow-up98%
Studies in flight10
98%
Reached
See the role ↗
06 / Governance
A five-member Research and Ethics Committee built from a blank page: quorum, SOPs, review workflows, post-approval oversight.

Ethics

Review · 2026
Members5
Risk–benefitReviewed
SAEs · DeviationsTracked
ClosureSigned
IRB
Chairperson
See the committee ↗

About

Research Studies Manager at Orthocure Medical Group, lecturer at Ajman University, chair of a research ethics committee, senior collaborator with the Global Burden of Disease study. MSc in Clinical Pharmacy at a 4.0 and BPharm, both summa cum laude.

Omar E. Hegazi

Correspondence

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